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چکیده
We sought to characterize WPEC by quantifying per-hour log-fold change. To do so, we regressed the log gene expression on time (hour) and extracted the linear slope. For genes with monotonically increasing or decreasing expression trajectories, the utility of our WPEC measure to discriminate is obvious. Our WPEC measure can also discriminate with more complex trajectories which may be reflective of the host genomic response to the initial injury and to the post-injury recovery. But inconsistent sampling timings across patients may have considerable effect, creating potential confounding. To increase the robustness and power of the analysis, it is useful to locate a time window such that the number of genes exhibiting reasonably monotonic trend increases.
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Negation detection in Swedish clinical text: An adaption of NegEx to Swedish
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Supporting Information S3. Mathematical analysis of difference equations of axon growth The monotonic growth of axons along the longitudinal direction In some particular cases the dynamical behaviour of solutions of system (main text Eq. 4) can be studied analytically to highlight certain important features of growing axons. In particular, it will provide a useful comparison between the generat...
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